The First Family is a family of space explorers and adventurers who are made up of Augustus and Julius, Nick and Natalie, Rex and Astra as well as Sasha and Karl. Together they fight interdimensional monsters, invent technology and study threats that no normal family could contain.
- Derelikt: One of the First Family's enemies is Derelikt, a space traveling villain who has had run-ins with the family in the past. Nothing is known about him other than the First Family's accounts of his actions.
- Gorilla Swarm
- Kaspian: The Prince of the Beastmen, biological father of Nick and Natalie, and grandfather of Sasha and Karl.
- Madame Majestrix
- Silver Brain
- Insectra: Little is known about Insectra.
- Ugly Max: Another one of the First Family's enemies is Ugly Max.
- Unholy Alliance
Astra Furst Augustus Furst Julius Furst Karl Furst Natalie Furst Nick Furst Sasha Furst Rex